Johnny Blaze was the adoptive son of a stunt rider, but his father was dying of cancer. One night Blaze met a mysterious man named Mephisto and they set up a deal. If Mephisto spared the life of Johnny's father, Johnny would give him his spirit. Johnny's father was cured of the cancer, but died in a failed stunt.

Blaze said that Mephisto didn't keep his end of the bargain, but Mephisto said he would only spare his life from the cancer and stripped Johnny of his spirit, thus turning him into a fiery ghost with a flaming skull for a head. Now whenever evil is sensed, Blaze turns into this monster, Ghost Rider, and rides and roams the streets, seeking vengeance against evil.

He has had several run-ins with Daredevil.